φάρμακο |
Etoposide |
Doxorubicin |
Cyclophosphamide |
granulocyte |
δόση |
50 (100) mg/m2 |
45 mg/m2 |
100 mg/m2 |
|
1 |
iv |
iv |
iv |
|
2 |
iv |
|
|
|
3 |
iv |
|
|
|
4 |
iv |
|
|
|
5 |
iv |
|
|
sc |
6 |
|
|
sc | |
7 |
|
|
|
sc |
8 |
|
|
|
sc |
9 |
|
|
|
sc |
10 |
|
|
|
|
21 |
κύκλος 21 ημερών |
φάρμακο |
ετοποσίδη |
ετοποσίδη |
doxorubicin |
cyclophosamide |
granulocyte |
|
δόση |
120 mg/m2 |
240 mg/m2 |
40 ng/m2 |
1000 mg/m2 |
|
|
1 |
iv |
|
iv |
iv |
|
|
2 |
|
po |
|
|
|
|
3 |
|
po |
|
|
|
|
14 |
|
|
|
|
|
φάρμακο |
doxorubicin |
cyclophosphamide |
vincristine |
neupogan |
δόση |
60 mg/m2 |
750 mg/m2 |
1.5 mg/m2 |
5 mg/Kg |
1 |
iv |
iv |
iv |
|
2 |
|
iv |
|
|
3 |
|
|
|
|
4 |
|
|
|
|
5 |
|
|
|
sc |
6 |
|
|
|
sc |
7 |
|
|
|
sc |
8 |
|
|
iv |
|
9 |
|
|
|
sc |
10 |
|
|
|
sc |
11 |
|
|
|
sc |
12 |
|
|
|
sc |
13 |
|
|
|
sc |
14 |
|
|
|
sc |
15 |
|
|
iv |
|
16 |
|
|
|
sc |
21 |
|
|
|
|
φάρμακο |
ετοποσίδη |
cisplatin |
Neulasta |
δόση |
100 mg/m2 |
25 mg/m2 |
5 mg |
1 |
iv |
iv |
|
2 |
|
iv |
|
3 |
iv |
iv |
|
4 |
|
iv |
|
5 |
iv |
iv |
|
6 |
|
|
sc |
7 |
|
|
|
21 |
κύκλος 21 ημερών |
φάρμακο |
ετοποσίδη |
καρβοπλατίνη |
Neulasta |
δόση |
120 mg/m2 |
300 mg/m2 |
5 mg |
1 |
iv |
iv |
|
2 |
iv |
|
|
3 |
iv |
|
|
4 |
|
|
sc |
5 |
|
|
|
28 |
κύκλος 28 ημερών |
φάρμακο |
Epirubicin |
cyclophosphamide |
Vincristine |
Neulasta |
δόση |
70 mg/m2 |
1000 mg/m2 |
2 mg |
|
1 |
iv |
iv |
iv |
|
2 |
|
|
|
sc |
21 |
|
|
|
|
κύκλος 21 ημερών |
φάρμακο |
ifosfamide |
carboplatine |
etoposide |
etoposide |
Vincristine |
Neupogen |
δόση |
5g/m2 |
300 mg/m2 |
120 mg/m2 |
240 mg/m2 |
0.5 mg/m2 |
5 mg/Kg |
1 |
iv |
iv |
iv |
|
|
|
2 |
|
|
iv |
|
|
|
3 |
|
|
|
po |
|
|
4 |
|
|
|
|
|
sc |
5 |
|
|
|
|
|
sc |
6 |
|
|
|
|
|
sc |
7 |
|
|
|
|
|
sc |
8 |
|
|
|
|
|
sc |
9 |
|
|
|
|
|
sc |
10 |
|
|
|
|
|
sc |
11 |
|
|
|
|
|
sc |
12 |
|
|
|
|
|
sc |
13 |
|
|
|
|
|
sc |
14 |
|
|
|
|
iv |
|
15 |
|
|
|
|
|
sc |
16 |
|
|
|
|
|
sc |
17 |
|
|
|
|
|
sc |
28 |
|
|
|
|
|
sc |
29 |
|
|
|
|
|
sc |
20 |
|
|
|
|
|
sc |
21 |
|
|
|
|
|
sc |
28 κύκλοι των 28 ημερών
|
φάρμακο |
topotecan |
Neulasta |
δόση |
1.5 mg/m2 |
5 mg/m2 |
1 |
iv |
|
2 |
iv |
|
3 |
iv |
|
4 |
iv |
|
5 |
iv |
|
6 |
|
sc |
21 |
|
|
21 κύκλοι 21 ημερών |
φάρμακο |
paclitaxel |
carboplatine |
Neulasta |
δόση |
200 mg/m2 |
AUC X 6 mg/ml/min |
mg/m2 |
1 |
iv |
|
|
2 |
|
iv |
|
3 |
|
|
sc |
20 |
|
|
|
φάρμακο |
gemsitabine |
cisplatin |
Neupogen |
δόση |
1000 mg/m2 |
100 mg/m2 |
5 mgKg |
1 |
iv |
|
|
2 |
|
iv |
|
3 |
|
|
|
4 |
|
|
|
5 |
|
|
|
6 |
|
|
sc |
7 |
|
|
sc |
8 |
iv |
|
|
9 |
|
|
sc |
10 |
|
|
sc |
11 |
|
|
sc |
12 |
|
|
sc |
13 |
|
|
sc |
14 |
|
|
sc |
15 |
iv |
|
|
16 |
|
|
sc |
28 |
|
|
|
φάρμακο |
cisplatin |
cyclophosphamide |
4-epidoxorubicin |
etoposide |
Neulasta |
|
100 mg/m2 |
400 mg/m2 |
40 mg/m2 |
100 mg/m2 |
6 mg |
1 |
|
iv |
iv |
iv |
|
2 |
iv |
iv |
|
iv |
|
3 |
|
iv |
|
iv |
|
4 |
|
|
|
|
sc |
κύκλοι 28 ημερών |
|
||||
|
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|